CBD is a naturally occurring non-psychotropic constituent extracted from the Cannabis plant. Its potential therapeutic benefits have been proven by many users, with pain relief being one of the benefits. However when it comes to science and medicine we need actual hard proof. There are some clinical trials happening to ascertain the abilities of CBD in managing pain and we will explore them in this article.
What is pain, clinically?
From a clinical viewpoint pain is the sordid sensory and emotional postulate influenced by real of perceived tissue infringement. It can be acute or intermittent. Acute pain often results from an injury or illness, and it is short lived, usually lasting for a few weeks. Pain is considered chronic if it persists for a period longer than three months. Some of the conditions that could cause this problem include arthritis, cancer, or a damage on the nerves.
How does CBD work?
A very brief and general over view: The endocannabinoid system (ECS) is a complex system that regulates a variety of bodily functions, such as pain, inflammation, and mood. CBD is assumed to interact with the ECS. This may assist in reduction of pain by inhibiting conduction of pain signals in the central nervous system.
What to know about CBD clinical trials with CBD as pain management.
Various clinical trials are currently in progress to test CBD’s effectiveness in reducing pain. A few of these trials include those targeting neuropathic pain and cancer associated pain. For instance, other trials are exploring the use of CBD in chronic pain.
What are the outcomes of the clinical trials?
Some of the clinical trials conducted on the use of CBD in the management of pain have had inconclusive results. The results of studies on the effectiveness of the CBD for pain are different. Additional studies are necessary to confirm the effectiveness of CBD in relieving pain.
Specific clinical trials on CBD for pain management:
A randomized, controlled trial of cannabidiol for chronic noncancer pain
This trial was published in the Journal of Pain in 2020. It found that CBD was effective in reducing pain and improving quality of life in patients with chronic noncancer pain.
Efficacy and safety of cannabidiol for chronic neuropathic pain: A randomized, controlled trial
This trial was published in the Lancet in 2015. It found that CBD was effective in reducing pain and improving quality of life in patients with chronic neuropathic pain.
Cannabidiol as a potential treatment for chronic pain: A review of preclinical and clinical data
This review was published in Frontiers in Pharmacology in 2019. It found that CBD has a number of potential therapeutic benefits for chronic pain, including pain relief, anti-inflammatory effects, and neuroprotective effects.
Cannabidiol for pain relief in advanced cancer
This trial was published in Journal of Clinical Oncology in 2020. It found that CBD was effective in reducing pain and improving quality of life in patients with advanced cancer.
A randomized, controlled trial of cannabidiol for the treatment of chronic lower back pain
This trial is currently ongoing. It is investigating the efficacy of CBD for chronic lower back pain.
These are just a few of the many clinical trials that are underway to investigate the efficacy of CBD for pain management. The results of these trials are promising, but more research is needed to determine the long-term efficacy and safety of CBD for pain.